WE LIVE IN kli-yug WHEREBY  HUMANKIND IS FORCASTED TO ENDEAVOUR ITS BEST TO FIND  viGNaan =  SCIENCE OF EMPIRICAL KNOWLEDGE ABOUT CREATION AND LIFE....   BY WHICH MONEY & MATERIAL WEALTH CAN BE MADE REGARDLESS IF SUCH SCINECE  WILL DESTROY LIFE ITSELF Examples of this viGNaan discovery with constant potential in humankind hands to self-destruct are: -  nuclear power but use in atomic weapons;nbsp; medical and genetic understanding which creates unlimited side effects to create more suffering but not curing diseases but just subduing disease symptoms - national a-  national and international governance systems which creates disillusion of benefit to humankind but ultimately through greed for wealth keeps 80 percent of the human population suffering system-slavery unto life-long individual, familial and communal suffering.... On this knowledge sharing PVAF web site has been shared as news and vED KNOWLEDGE a lot of KNOWLEDGE OF TRUTH called GNaan in sNskRUt language vs viGNaan talked about above....TO MAKE YOUR TOMORROW HAPPIER THAN TODAY WITH TRUE KNOWLEDGE..... Today, on the next page, an example of the continuing viGNaan's life-destroying potential but wealth producing potential for the greedy is published....through a news of the up and coming pill which when taken would make your body muscles function as if you were doing physical exercise which is required to keep you healthy in a natural way.....although at this stage it has worked on mice just most of other pharmaceutical discoveries...humans will find a way to work on your body....but they will tell you about its debilitating harmful negative side after the greedy humans have made money off you to get wealthy at the expense of your natural good health gift from your Creator.....

Couch potato HI-SI fantasy: exercise in a pill........ span>Drug offers plenty of promise, potential for abuse Edmonton Journal: 1 Aug 2008:  MARGARET MUNRO Exercise in pill form was unveiled Thursday — along with a warning that Olympians in Beijing could be tested for abusing the medications that transform mice into long-distance runners. The drugs “gThe drugs “genetically reprogram” muscle fibres, mimicking many of the effects of exercise, say researchers who describe the impact on rodents as “stunning.” There is a good chance the drugs will work in humans and enable athletes to boost their endurance, says molecular biologist Ronald Evans, who heads the team at the Salk Institute in California. He also envisions the drugs giving couch potatoes a workout and helping bed-ridden individuals stay in shape. His team is reporting in the journal Cell that mice given the experimental medications ran up to a kilometre, or 68 per cent, farther than untreated mice. The drugs, which are taken orally, are readily available from laboratory supply companies. While not approved for human use, there is concern some athletes may already be taking them to try to shave time off their races. The World Anti-Doping Agency is aware of the possibility and has been working with Evans “to develop and implement ways to detect these molecules,” says Frederic Donze, senior media relations manager for the Montreal-based agency that will check for a longlist of performance-enhancing drugs in Beijing. The molecules, known as GW1516 and AICAR, mimic many of the physiological effects of exercise, says Evans, who describes them as “exercise pills” that trick muscles into “believing” and performing as if they have been working out. r /> In their research paper, they describe how the drugs genetically reprogram muscle fibres to burn fat and contract repeatedly without fatigue. In what Evans describes as a “couch-potato experiment” they treated sedentary mice with AICAR for a month before putting them on a treadmill. Remarkably, the treated mice ran almost 600 metres in 40 minutes, or 44 per cent longer, than untreated mice. They report GW1516 had an even more dramatic effect, but only when coupled with exercise. The scientists had mice run 30 minutes a day for a month, with one group also receiving GW1516. When the mice were put on the treadmill after four weeks, the GW1516treated mice ran more than three hours and three kilometres, or 68 per cent farther than the mice that had only done exercise training. . Trials to test how the drugs affect human muscles and endurance have yet to start, but Evans said in an interview that there is “a very good chance” there will be a similar response in humans. Several companies already distribute the compounds for use in research, including Toronto Research Chemicals Inc., which sells AICAR for $120 a gram. Evans sees plenty of potential for use, and abuse, of the drugs to try to improve endurance. “We’re not trying to bypass the need to exercise,” says Evans. “But the idea that you could have exercise in a pill has a lot of potential benefits and could have widespread and valuable use.” He says the drugs might offer “a jump start” to people who are so obese they cannot exercise and might also counter the muscle-wasting effects of aging and diseases such as muscular dystrophy. Couch potatoes and people who simply don’t get enough exercise might also benefit by popping a pill while watching TV, he says. The sporting world has long been aware of the work in Evans’s lab, which made international headlines in 2004 by genetically engineering a “marathon mouse” that ran twice as far as normal mice. The mouse was made by enhancing the activity of a gene called PPARdelta, which regulates many of the genes in muscle. The marathon mouse raised much concern about “gene doping” by athletes. But reprogramming genes in humans is complicated, dangerous, unethical, and likely still years away, says UBC’s Rupert, who is working to devise a gene-doping test for the World Anti-Doping Agency. AICAR and GW1516 promise a much easier way to rev up muscle genes as the compounds work on the same genetic pathways used to create the marathon mouse. They provide a chemical signal that “reprograms the skeletal muscle genome and dramatically enhances endurance,” Evans’s group reports. Anti-doping officials are trying to stave off abuse. The anti-doping agency received “key information” from Evans in order to develop and implement ways to detect the molecules, says Donze. The agency is not revealing whether it will test for AICAR and GW1516 in Beijing

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