|EXTREME CUTTING-EDGE SCIENCE OF NANOTECHNOLOGY....is revealing the inherent creative and operational powers of Life created by Nature and its Creator.|
Posted by Champaklal Dajibhai Mistry on August 21, 2012
.....TODAY IN THE PHOTO BELOW
YOU ARE LOOKING AT
THE ATOMS OF PURE GOLD....
.......for most of us for the first
|Image of surface
reconstruction on a clean
(100) surface, as visualized using
scanning tunneling microscopy. The individual atoms composing the
material are visible. Surface reconstruction causes the surface atoms to
deviate from the bulk crystal structure, and arrange in columns several
atoms wide with regularly-spaced pits between them.
(Atomically resolved STM image of
clean Au(100). This image is made with an Omicron Low Temperature STM
and RHK Technology electronics by Erwin Rossen, Eindhoven University of
Technology, 2006. Parameters: p<1e-11 mbar, T=77 K, I_setpoint=6 nA,
V_bias=1 mV, Au(100) surface is Ar sputtered (1,5 kV, 2uA, 30 minutes)
and annealed (500°C, 30 minutes)).
|Nanotechnology was a term
popularised by K. Eric Drexler’s highly influential work of speculative
nonfiction Engines of Creation (1987), often abbreviated to ‘‘nanotech’’
and readily giving rise to such derivatives as ‘‘nanoware’’ and ‘‘nanobots’’
(nanotechnological robots). Engines of Creation summarised a train of
thought that Drexler had first set in motion in ‘‘Molecular Engineering:
An Approach to the Development of General Capabilities for Molecular
Manipulation’’ (1981), although similar ideas had previously been
broached in Richard Feynman’s essay ‘‘There’s Plenty of Room at the
Bottom’’ (1961, in H. D. Gilbert’s Miniaturization). Nanotechnology is a
drastic extrapolation of the notion of technological miniaturisation,
proposing the development and use of extremely tiny machines capable of
manipulating individual atoms and molecules, simulating and vastly
extending the ‘‘natural molecular technologies’’ used by living cells to
manufacture proteins, organs, and whole bodies.....click
here to keep on
ALSO KNOW THAT....
...THAT children younger than two
wwill not reject a heart from a donor with a different blood type...
| ....THAT stealth nano-particles with
the antigens, or markers, br />
that blood cells use to recognize each other,
when introduced into the bloodstream can teach
the body to tolerate
every blood type....
.....An with this technology, the nano-particles could eventually be in
the standard set of shots that children receive.
Later, if you ever had to have an organ transplant or a transfusion,
you wouldn’t have to wait for the right blood type one
– you could just take any donor organ....
-says Dr. Buriak, a senior research officer at
National Institute for Nanotechnology
who hopes to move to more advanced models by 2015...
|.....And there is more similar exciting
Life-Knowledge discovery news
from the evolving world of
PVAF share with your today...Life-Knowledge to give hope for the
potential to take away many of the life's suffering and pain with
Knowledge of how life works through Life-sciences .......and as usual to base your hope on realistic
life expectations do not forget to click on the hyperlinked words to learn
the Life-sciences thereof to the depth that suits your lifestyle
|....just click on the next line to go to the next webpage for your
knowledge quest today..
TODAY'S SHARING OF
EVOLVING CUTTING-EDGE KNOWLEDGE .....
.....the future of which is a potential for
human poverty of physical suffering and pain at
....where every things exists with a probability....
.....the human spirit of
is what keep life on a path to prosperity of
continually removing all life poverties...
|....and through Innovation....
your doctor’s office.....
Globe and Mail:
October 4, 2011: Nick Rockel)
(...in-depth KNOLWEDGE providing hyperlinks,
photos and term explanations in small font italics were
PVAF as per its mandate to spread Life-sciences Knowledge to entire
on the timeless borderless internet plateform...
PLEASE USE THIS SERVICE TO MAKE YOUR
TOMORROW HAPPIER THAN TODAY SIMPLY BECUASE
"KNOWlEDGE SHALL SET YOU FREE FROM
ALL LIFE POVERTIES"....)
Jillian Buriak’s laboratory, it’s
a small world.
Dr. Jillian Buriak
(Globe and Mail
A University of Alberta chemistry professor and a senior
research officer at Edmonton’s
National Institute for Nanotechnology
(NINT), Dr. Buriak manipulates
silicon and other materials at the
scale – between one and 100
nanometers in size.
Just how tiny is that?
Think of it this way: A grain of sand measures one million nanometres
Dr. Buriak is one of many scientists who are applying
medicine. Since 2005, she has worked with a
trying to solve the problem of
rejection in organ transplants due to
People keep asking when her field will deliver a killer app like the
cure for cancer.
Dr. Buriak says. “But what nanotechnology has done more
than anything else is bring people together who normally would never
talk to each other,” she explains.
Over the past decade, nano-medicine has moved out of the research lab
and into the doctor’s office, in products such as anti-cancer drugs and
wound dressings. But scientists are just starting to tap its potential
for everything from drug delivery to disease diagnosis.
One of Dr. Buriak’s key collaborators on the transplantation project is
Lori West, a U of A professor of pediatrics, surgery and immunology. Dr.
West, a renowned cardiac transplant expert, is known for her discovery
that children younger than two will not reject a heart from a donor with
a different blood type.
Dr. Lori West, MD.
That’s because the immune system is still developing during infancy.
Even more remarkably, if a baby with Type A blood gets a Type B heart,
it will develop a lifelong tolerance for B and AB blood.
The U of A team “functionalized” so-called stealth
the antigens, or markers, that blood cells use to recognize each other.
In animal tests, it introduced these particles into the bloodstream in
an attempt to teach the body to tolerate every blood type.
Dr. Buriak, who hopes to move to more advanced models by 2015, says the
nano-particles could eventually join the standard set of shots that
children receive. “Later, if you ever had to have an
a blood transfusion, you wouldn’t have to wait for the right one – you could
just take any of them.”
At the University of Toronto, chemist Shana Kelley leads nanotech
research that includes better disease testing. Dr. Kelley, who works
across four U of T faculties, says widespread adoption of
is on the horizon. With all
paradigm shifts in science, Dr. Kelley
explains, practical applications gain momentum after a long period of
basic research. “There’s an inflection point, and I think we’re nearing
that inflection point.” ("Inflection
point" means:An event that results in a significant change in the
progress of a company, industry, sector, economy or geopolitical
situation. An inflection point can be considered a turning point after
which a dramatic change, with either positive or negative results, is
expected to result. Companies, industries, sectors and economies are
dynamic and constantly evolving. Inflection points are more significant
than the small day-to-day progress that is made and the effects of the
change are often well-known and widespread.)
For seven years, Dr. Kelley and her colleagues have been developing nano-scale
sensors for biomarkers of cancer and other diseases. They’ve found a way
to print nano-materials on the surface of microchips, then attach these
sensors to molecules that will bind to the samples they want to test.
“There’s a dramatic difference [from] using a nano-material-based sensor
versus a more conventional type of sensor,” Dr. Kelley says. “It allows
you to get right down to very low levels of the molecules that are
markers of disease.”
Dr. Kelley’s group has already filed patents, licensed its intellectual
property and started a company. The next step: two years of development
work to make the technology robust enough for approval by
U.S. Food and Drug Administration. “Then it may just be a few
months away from being able to let
clinicians use it,” she says.
Meanwhile, scientists at the
Argonne National Laboratory near Chicago
are fighting disease with nanotech. At the laboratory’s Center for Nanoscale Materials, the NanoBio Interfaces Group began by integrating
titanium dioxide nano-particles with
biomolecules so it could target
sites in unwanted cells and destroy the cells by applying
It then added cell-killing
magnetic material to its repertoire
Having proven that this method works against dental
illnesses such as psoriasis, group leader
Dr. Tijana Rajh and her team are
now focusing on brain
head and neck cancer. “It could be applied in
whatever we want to get rid of specifically in
the body, we can do it,” says assistant scientist
Dr. Tijana Rajh
; Photo Right:
Elena Rozhkova. (click each name for her work
and personal biography)
Toronto-based Tornado Medical Systems, a medical imaging and
spectroscopy startup, plans to unveil its first nano-medicine prototype
next January. Current spectrometers are bulky, expensive instruments
that rely on lenses, mirrors and fibre optics. But the next generation
will be on computer chips, says molecular geneticist Frédéric Sweeney,
Tornado’s vice-president for business development and strategy.
The company has developed a chip-sized nano-photonics
technology licensed from Cornell University electrical and computer
Dr, Michal Lipson. Spectrometers on chips are more
durable and much cheaper to produce, says Dr. Sweeney, who notes that
Tornado also has ideas for diagnostic tools to follow its imaging
Dr. Michal Lipson
PhD (Physics, 1998)Cornell
University electrical and computer engineering professor.
Lipson's group investigates the physics and application of nanoscale
photonic structures. In particular we are interested in light confining
structures that can slow down, enhance and manipulate light. These
structures can enhance light-matter interaction by orders of magnitude,
enabling the devices; optical properties to be controlled externally,
either optically or electro-optically. The structures developed will
provide the basic building blocks for an all-optical circuit where
passive as well as active components could be integrated on a single
Within a decade, he hopes, physicians will have point-of-care tests for
diagnosing heart attacks and other conditions on the spot. “If we can
develop tests that allow us to make these go/no-go decisions much
faster, I think it’s going to significantly increase efficiencies in
hospitals,” Dr. Sweeney says.
Back in Edmonton,
David Wishart thinks
the most interesting nano-scale
devices are biological systems. Dr. Wishart, a professor in the
University of Alberta’s departments of computer science and biological
science, heads nano life sciences research at NINT.
Dr. David Wishart
Among other projects, his group has created
nano “robots” by altering
the genetic makeup of bacteria so they change colour when exposed to
certain chemicals. Building on existing “lab on chip” technology, Dr. Wishart aims to install such biosensors on a device the size of a USB
key. After inserting a blood, urine or water sample into this portable
lab, the user could read the results on a laptop.
Dr. Wishart laments the lack of progress in modernizing medical testing
through nano and other new technologies. “They’ve all basically died,
partly because of the red tape but also the lack of interest or vision
or motivation by the medical community,” he says. “We just don’t have a
process in North America or even in Europe to get these things into
Here are three commercially available nano-medicine products, from the
online inventory of the Washington-based
Project on Emerging
Abraxane, a cancer treatment:
Developed by Los Angeles-based Abraxis BioScience Inc., it won approval
from the Food and Drug Administration in 2005. It targets advanced
breast cancer by delivering its active agent in a nanoparticle coating.
Vitoss, for bone replacement:
Surgeons use this
synthetic biomaterial/a> from
Inc., a Pennsylvania-based
biosurgery company, to
perform bone grafts..
for wound dressing:
Introduced in 1998, this antimicrobial barrier dressing/a> contains
Smith & Nephew licenses Acticoat’s technology from
Nucryst Pharmaceuticals Corp., a company that does
research and development and manufacturing in Fort Saskatchewan, Alta.
.......and now just to needle your inquisitiveness....
befor you say Goodbye PVAF today.....
did you know this of our known human history.....
human organ transplantation....
|Roman Catholic accounts report the
Cosmas as replacing the
gangrenous leg of the Roman deacon
Justinian with the leg of a recently deceased
Ethiopian.. SeveraL apocryphal accounts of transplants exist
well prior to the scientific understanding and advancements that would
be necessary for them to have actually occurred. The Chinese physician
Chi'ao reportedly exchanged hearts between a man of strong spirit
but weak will with one of a man of weak spirit but strong will in an
attempt to achieve balance in each man. Most accounts have the saints
performing the transplant in the 4th century, decades after their
deaths; some accounts have them only instructing living surgeons who
performed the procedure. The more likely accounts of early transplants
deal with skin transplantation. The first reasonable account is of the
Sushruta in the 2nd century BC, who used autografted skin
transplantation in nose reconstruction
rhinoplasty....read the comprehensive overview of history of organ
transplantation from antiquity to todate by clicking
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